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Choice of preparations by animal species

  1. horse
  2. cow
  3. goat
  4. sheep
  5. pig
  6. dog
  7. cat
  8. rabbit
  9. fur-bearing animals
  10. turkey
  11. chicken
  12. duck
  13. goose
  14. dove

Normotel

Suitable for:

cow

Normotel

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Normotel

oral solution

 

Composition

1 ml of the feed additive contains:

propylene glycol — 0.78 ml

methionine — 15 mg

choline chloride — 15 mg

nicotinamide — 15 mg

cyanocobalamin — 0.001 mg

calcium pantothenate — 0.3 mg

zinc — 3 mg

selenium — 0.03 mg

cobalt — 0.015 mg

 

Description

Transparent, colorless or light pink liquid.

 

Pharmacological properties

The combination of propylene glycol, methionine, a complex of B vitamins and essential elements raises energy potential, stimulates metabolic processes in cows prone to ketosis.

Propylene glycol reduces the molar ratio of acetic and propionic acids in cow rumen, concentration of free fatty acids and beta-hydroxybutyrate, concentration of triacylglycerols in liver, and concentration of ketone bodies in milk. Increases reproductive efficiency of animals, energy balance of cows during early lactation, helps to increase milk yield.

Methionine is an essential amino acid, which has a metabolic, hepatoprotective effect, participates in the exchange of sulfur-containing amino acids, as well as in synthesis of epinephrine, creatinine and other biologically important compounds; activates action of hormones, vitamins, enzymes, proteins; reduces concentration of cholesterol and increases the concentration of blood phospholipids.

Choline chloride conditionally belongs to the vitamins of group B, plays an important role in the metabolism of phospholipids and their synthesis in liver.

Nicotinamide is involved in the metabolism of fats, proteins, amino acids, purines, tissue respiration and glycogenolysis.

Cyanocobalamin as a metabolite activates the metabolism of carbohydrates, proteins and lipids, promotes the synthesis of labile groups in the formation of choline, methionine, nucleic acids, normalizes the liver function and nervous system, activates blood clotting.

Calcium pantothenate is easily absorbed in the intestine and cleaves, releasing pantothenic acid, which is an indispensable structural component of coenzyme A, which plays an important role in metabolic processes — the synthesis and oxidation of fatty acids, the Krebs cycle and other biochemical reactions.

Zinc is involved in the exchange of nucleic acids and the synthesis of proteins.

Selenium is an essential nutrient, it is a component of various antioxidant enzymes that are responsible for protecting cell wall lipids from peroxidation.

Cobalt is involved in blood formation, it is a catalyst for a number of enzymes, promotes the biosynthesis of vitamin B12 intestinal microflora in the small intestine.

 

Indications

It is indicated for the treatment of pregnant and lactating cows in case of subclinical and clinical ketosis, prevention of cows before and after calving in order to increase productivity and normalize metabolism.

 

Contraindications

Do not administer to cows with hypersensitivity to the active ingredients of the feed additive.

 

Administration and dosage

The drug is administered individually with fodder or water or undiluted using drencher or probe in the following doses:

• stimulation of metabolism in pregnant cows and ensuring the normal course of the postpartum period — 300-400 ml per animal, the course — 2-3 days before calving and 2 days after calving;

• prevention and treatment of subclinical and clinical ketosis, preferably at 2-6 week of lactation, depending on the degree of metabolic disorders — 300-400 ml per animal, the course — 4-5 days.

 

Warning

In case of large overdose in animals the decreased appetite, decrease of water consumption, gastrointestinal disorder may be observed.

 

Packaging

Polymeric vials of 2 l, polymeric cans of 20 l.

 

Storage

Store in a dry, dark place at the temperature from +5 °C to +25 °C.

After opening of vial the drug must be used within 30 days, the feed additive solution in water — within 48 hours.

 

Shelf life

2 years.