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Lidocaine hydrochloride

Suitable for:

horse cow goat sheep pig dog cat

Lidocaine hydrochloride

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Lidocaine hydrochloride

solution 2% for injections



1 ml of the medicinal product contains:

lidocaine hydrochloride — 20 mg



Colorless, transparent liquid.


Pharmacological properties

Lidocaine hydrochloride — is an acetanilide derivative, belongs to the group of amino amide medicinal products for local anesthesia, which deprive painful sensitivity of the restricted area of the body. The action is to stabilize the neuronal membrane, reduce its permeability for sodium ions, which prevents the impulses along nerve fibers. Antagonism with calcium ions is possible. It is quickly hydrolyzed in a slightly alkaline environment of tissues and after a short latent period, it lasts for 60-90 minutes. The anesthetic effect is 2-6 times stronger than procaine but decreases in case of tissue acidosis. It is effective with all types of local anesthesia, has moderate vasodilation and sedative properties.

In case of intramuscular injection, the maximum concentration in the blood is reached in 5-15 minutes, the anesthetic effect begins in 2-5 minutes and lasts about 90 minutes. In case of local administration, the solution is absorbed for 7-20 minutes, depending on the dose and site of application. In blood plasma it binds to proteins by 50-80%, is metabolized in the liver and is excreted in 4-5 hours by kidneys mainly in the form of metabolites.



It is indicated for cattle, sheep, goats, horses, pigs, dogs, cats for all kinds of local anesthesia (superficial, infiltration, conductive, epidural, spinal, intraarticular), blockades of peripheral nerves, nerve plexuses in case of pain syndromes and acute inflammatory processes.



Do not administer to animals with increased sensitivity to lidocaine and other amide medicinal products, during pregnancy, in case of severe bleeding or infection of possible injection sites, diseases of the cardiovascular system, impaired liver function accompanied by a decrease in hepatic blood flow.


Administration and dosage

The medicinal product is used in the form of solutions of 0.25, 0.5 and 1% for the preparation of which 7, 3 or 1 part of water for injections are respectively injected into a syringe to one part of lidocaine hydrochloride.

The maximum permissible dose of lidocaine hydrochloride per active ingredient per 1 kg of body weight is: for cats — 2 mg; for cattle, sheep, goats, horses, pigs, dogs — 4 mg.

Doses and concentrations of lidocaine hydrochloride solution for various purposes are indicated in the table.



Solution of medicinal product, %

Dose, ml/1 kg of body weight

cattle, sheep, goats, horses, pigs, dogs


Infiltration anesthesia




Therapeutic blockade




Superficial anesthesia of skin covering, mucous and synovial membranes, conductive, epidural anesthesia







Spinal anesthesia





To prolong the action of anesthetic, 0.1 ml of adrenaline solution 0.1% is added to every 10 ml of lidocaine hydrochloride solution.



Carefully prescribe to animals with liver disease, congestive heart failure, in a state of shock and hypovolemia with severe respiratory depression, hypoxia, during lactation. In the latter case, the medicinal product is used only when the intended benefit for the female exceeds the potential risk for the young animals.

Do not mix with other products in the same syringe. Do not combine with barbiturates, curare-like drugs, with medicinal products that suppress or excite central nervous system.

When using in therapeutic doses, side effects are not observed, however, from the side of the nervous system and sense organs, oppression or excitation, disorientation, vomiting, sweating, visual impairment, tremor, convulsions, respiratory depression, apnea are possible. After the administration of large doses of the medicinal product, the decrease of arterial pressure, bradycardia, arrhythmia, shock, cardiac arrest and sometimes allergic reactions are possible.

When a needle hits the vessel and lidocaine enters the bloodstream, a collapse may occur. In this case, vasoconstrictive and cardiac agents are used.

In case of an overdose of the medicinal product, drowsiness, visual impairment, vomiting, decrease of arterial pressure, tremor of muscles are possible. In case of rapid injection, the hypotension, vascular collapse, convulsions, oppression of the respiratory center occur. Allergic reactions with the onset of anaphylactic shock are possible. In case of a decrease in the heart rate, 0.5-1 mg of atropine sulfate is allowed.



Glass ampoules of 2 ml, glass vials of dark color of 10 ml (10 pieces in a cardboard box).



In the manufacturer's packaging, in a dry, dark place at a temperature from +3 °C to +25 °C.

The medicinal product should be stored in the refrigerator and used within 10 days of opening.


Shelf life

3 years.