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Choice of preparations by animal species

  1. horse
  2. cow
  3. goat
  4. sheep
  5. pig
  6. dog
  7. cat
  8. rabbit
  9. fur-bearing animals
  10. chicken
  11. duck
  12. goose
  13. сamel

Tricillin

Suitable for:

cow

Tricillin

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Tricillin

powder for external use

 

Composition

6 g (1 vial) contain:

benzylpenicillinum-natrium/calium — 500 000 U

streptomycin sulphat — 500 000 U

streptocide white — 5 g

 

Description

White fine powder with specific odor.

 

Pharmacological properties

Combined drug with a wide spectrum of antimicrobial action against Gram-positive microorganisms Streptococcus spp., Staphylococcus spp., Clostridium spp., Bacillus spp., Corynebacterium diphtheriae, Gram-negative E. coli, Salmonella spp., Shigella spp., Yersinia spp., Klebsiella spp., Haemophillus influenzae, Neisseria gonorrhoeae, Neisseria meningitidis, Francisella tularensis, Brucella spp., Proteus spp., Pasteurella spp., Bordetella spp., anaerobe Escherichia coli, as well as Proteus spp., Klebsiella spp., Enterobacter spp., Corynebacterium diphtheriae, Neisseria spp., Peptostreptococcus spp., Clostridium spp., Listeria monocytogenes, Treponema, Borrelia, Leptospira.

Benzylpenicillin is a bactericidal antibiotic from the group of natural penicillins that prevents formation of peptide bonds by inhibiting activity of transpeptidase, violates the late stages of synthesis of the cell wall peptidoglycan, which leads to lysis of dividing cells.

Streptomycin — an aminoglycoside antibiotic with a broad spectrum of antimicrobial action, binds to the 3OS-subunit of the bacterial ribosome, which leads to suppression of protein synthesis in microorganisms.

Streptocide refers to sulfonamides, acts bacteriostatic, preventing use of para-aminobenzoic acid by microorganisms for synthesis of dihydrofolic acid, which is involved in synthesis of the pyramidine bases of DNA and RNA of microbial cells.

 

Indications

It is indicated for prevention and treatment of cows suffering from thelaziosis, keratoconjunctivitis, as well as post-partum complications, various wounds of the skin, caused by microorganisms sensitive to penicillin, streptomycin and streptocide.

 

Contraindications

Do not administer to animals sensitive to the active ingredients of the drug. Do not administer to animals with impaired liver and kidney function.

 

Administration and dosage

If detention of the afterbirth is observed in cows, the drug is used 12-24 hours after calving. Before the introduction of the drug, sanitize the external genital organs, the root of the tail, released part of the placenta, and conduct the aseptic treatment (with sodium hypochlorite solution, rivanol, etc.).

The veterinarian exposes the arm to the shoulder and treats it as before the operation, according to the general surgery instructions, puts on a sterile rubber or polyethylene obstetric glove and injects 6 g of the drug intrauterinely and 2 g in the vagina under the placenta.

Then, conduct sanitary and aseptic processing of the external genital organs, released part of the placenta daily; inject 2 g of the drug under the placenta and into the vagina, daily. Intrauterine drug is administered every 48 hours at the same dose until complete separation of the placenta. If the afterbirth is not separated within 3 days from the start of the treatment, it is removed manually, then 6 g of the drug is administered, after 48 hours the drug is re-administered at the same dose.

In complicated births and trauma of the birth canal, 3 g of the drug is prophylactically administered to the uterus.

 

Warning

Slaughter of animals for meat is allowed in 7 days after the last administration of the drug, milk — in 3 days.

Milk and meat obtained earlier that the specified period must be utilized or fed to non-productive animals depending on a conclusion of the veterinarian.

 

Packaging

Glass vials of 6 g.

 

Storage

Store in a dry, dark place at the temperature from +4 °C to +20 °C.

 

Shelf life

2 years.