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Choice of preparations by animal species

Brovaseptol powder

Suitable for:

cow

sheep pig

rabbit

turkey chicken duck goose

Brovaseptol powder

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Brovaseptol powder

powder for oral use

 

Composition

1 g contains:

sodium sulfathiazole — 80 mg

sulfaguanidine — 70 mg

trimethoprim — 30 mg

oxytetracycline hydrochloride — 45 mg

tylosin tartrate — 25 mg

 

Description

Light yellow powder, slightly soluble in water.

 

Pharmacological properties

Complex bactericidal and bacteriostatic drug of a wide spectrum of action.

Tylosin tartrate — an antibiotic from the macrolide group, by irreversible connection with the subunit 50S of bacterial ribosomes inhibits protein synthesis, growth and multiplication of the microbial cell. Effective against Gram-positive and certain Gram-negative bacteria — Corynebacterium spp., Clostridium spp., Erysipelothrix spp., Pasteurella spp., Vibrio spp., Leptospira spp., Brucella spp., Neisseria spp., Haemophilus spp.., rickettsia Rickettsia spp., Spirochete Spirochaetes, mycoplasmas M. gallisepticum, M. synoviae, M. meleagridis etc.

Sulfatiazole is an antimicrobial bacteriostatic agent, active against Gram-positive and Gram-negative bacteria — E. coli, Shigella spp., Klebsiella spp., Vibrio cholerae, Clostridium perfringens, Corynebacterium diphtheriae, Yersinia pestis, Chlamydia spp., Actinomyces israelii, Toxoplasma gondii.

Sulfaguanidine is an antimicrobial bacteriostatic sulfonamide substance that inhibits dihydropteroate synthetases, which leads to a disruption in the synthesis of tetrahydrofolic acid necessary for the synthesis of purines and pyrimidines.

Oxytetracycline is a bacteriostatic antibiotic, it breaks protein synthesis when interacting with ribosomes, reduces the permeability of the cytoplasmic membrane of microorganisms. Works against Gram-positive and Gram-negative bacteria — Streptococcus spp., Clostridium spp., Corynebacterium spp., Brucella spp., Haemophilus spp., E. coli, Pasteurella spp., Klebsiella spp., Fusobacterium spp., Salmonella spp., as well as Protozoa, Mycoplasma spp., Rickettsia spp., Chlamydia.

Trimethoprim is a chemotherapeutic agent that acts against Gram-positive bacteria Staphylococcus spp., Streptococcus spp., Clostridium spp., Corynebacterium spp. etc, Gram-negative bacteria E. coli, Salmonella spp., Klebsiella spp., Proteus spp., Pasteurella spp., Bordetella spp. etc., inhibits bacterial reductase that converts dihydrofolic acid to tetrahydrofolic acid, which is necessary for synthesis of purines and nucleic acids.

 

Indications

It is indicated for treatment of animals affected by diseases of the digestive tract, respiratory and urogenital systems, namely:

• calves (up to 3 months age) — treatment of animals suffering from gastroenteritis, salmonellosis, pasteurellosis;

• pigs — treatment of animals suffering from enzootic pneumonia, arthritis, dysentery, edema disease, erysipelas, salmonellosis, pasteurellosis;

• sheep (up to 3 months age) — treatment of animals suffering from septicemia, eimeriosis;

• rabbits — gastroenteritis, colibacteriosis, pasteurellosis, pneumonia;

• poultry (chickens, turkeys, ducks, geese) — panleukopenia, cholera, salmonellosis, mycoplasmosis, rhinitis.

 

Contraindications

Do not administer to animals with hypersensitivity to sulphathiazole, tylosin, oxytetracycline, sulfaguanidine, trimethoprim, as well as with liver and kidney diseases. Do not use for milk cows and laying hens, whose milk and eggs are used for human consumption.

 

Administration and dosage

Orally with feed.

Treatment of pigs, poultry and rabbits is primarily conducted by the group method by uniformly mixing the daily amount of feed with the drug at the following doses (up to 100 kg of feed):

• pigs — 300-350 g;

• poultry, rabbits — 400 g.

Daily dose for all types of animals is 1.0-1.2 g per 10 kg of body weight.

The daily dose is administered in two steps, treatment course is 3-6 days. Depending on the state of the disease the first dose may be increased for 30-100%, treatment course may be extended for 1-2 days.

 

Warning

Slaughter of animals and poultry for meat is allowed in 8 days after the last treatment. Meat obtained before specified period is fed for unproductive animals depending on a conclusion of a veterinarian.

 

Packaging

Polymer packages of 12 g, 36 g, 100 g, 500 g.

 

Storage

Store in a dark place, out of children reach at a temperature from +4 °C to +25 °C.

 

Shelf life

2 years.