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Choice of preparations by animal species

Brovaseptol concentrate

Suitable for:

horse cow

sheep pig dog cat rabbit

turkey chicken duck goose

Brovaseptol concentrate

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Brovaseptol concentrate

powder for oral use

 

Composition

1 g contains:

sulfadimetoxin sodium salt — 300 mg

sulfadiazine sodium salt — 300 mg

trimethoprim — 120 mg

 

Description

Homogeneous powder of light-yellow color with light characteristic smell, water-soluble

 

Pharmacological properties

The combined antibacterial preparation of a wide spectrum of action.

Sulfonamides and trimethoprim (a derivative of diaminopyrimidine) block enzymes in two consecutive stages of the biosynthesis of folic acid in a bacterial cell, which leads to suppression of bacterial growth, cessation of their reproduction and death. The combination of active ingredients in the preparation reduces the likelihood of the emergence of resistant forms of pathogenic microflora.

Acts against Gram-positive and Gram-negative bacteria Staphylococcus spp., Streptococcus spp., Neisseria spp., Clostridium spp., Listeria monocytogenes, Corynebacterium spp., E. coli, Salmonella spp., Klebsiella spp., Proteus spp., Citrobacter spp., Pasteurella spp., Bordetella spp, Enterobacter spp., Yersinia enterocolitica, Chlamidya spp., Vibrio cholerae etc., some protozoans Pneumocystis carinii, Coccidia, Toxoplasma.

Sulfanilamides are quickly distributed throughout the body, their therapeutic concentration is maintained in serum for 25 hours. Their concentration in kidneys is higher, and in skin, liver and lungs is lower than in blood plasma.

Trimethoprim is rapidly distributed throughout the body, its maximum concentration is reached 4 hours after injection. Concentration in lungs, liver and kidneys is higher than in blood plasma.

Sulfonamides and trimethoprim are excreted by kidneys through glomerular filtration and tubular secretion. A small amount is metabolized in liver and is excreted with bile.

 

Indications

It is indicated for treatment of calves and lambs (up to 6 weeks of age), horses, pigs, rabbits, dogs and cats, poultry suffering from the diseases of the digestive tract (gastritis, enteritis, dyspepsia), respiratory organs (tonsillitis, tracheitis, pharyngitis, pneumonia, pleurisy) and genitourinary system (puerperal sepsis, cystitis, urethritis, endometritis), postoperative complications, as well as animals suffering from mastitis, actinomycosis, erysipelas, dysentery, diplococcus, enterotoxaemia , eimeriosis, colibacillosis, pasteurellosis, pullorosis, edematous disease, mycoplasmosis, salmonellosis.

 

Contraindications

Hypersensitivity to the drug. Do not administer to animals with impaired renal function and liver, ruminant animals with functionally formed proventriculus.

Do not administer to laying hens, eggs of which are used as food.

 

Administration and dosage

Orally with drinking water or feed in a dose — 0.3-0.35 g of drug per 10 kg of body weight one or two times a day.

For poultry and rabbits the dose is 1 g per 3 l of water, the course of treatment — 4-6 days. Veterinarian, depending on the intensity of the disease and the clinical condition of the animals, may increase the dose of the first administration for 30-50% and extend the course of treatment for 2-3 days.

 

Animal species

Body weight, kg

Age, week

Daily dose, g

per 100 l of water

per 100 kg of feed

Sucking piglets

under 10

 

35-50

120-150

Weaned piglets

11-25

 

25-35

65-80

Breeding pigs

26-100

 

35-45

80-110

Sows

over 150

 

150-180

Chickens, turkeys, geese, ducks (young poultry)

 

under 1

13-15

 

1-8

17

34

 

9-18

25

50

Broiler chickens

 

1-4

15-18

30-33

 

5-8

25

42

 

Warning

Slaughter of calves, sheep, pigs, rabbits for meat is allowed in 4 days, of poultry — in 2 days.

 

Packaging

Polymer packages of 5, 25 g, 1 kg.

 

Storage

Store in a dark place, out of children reach at the temperature from +8 °C to +25 °C.

Prepared solution should be used within 1 day. If it’s stored in the fridge — within 3 days.

 

Shelf life

2 years.