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Choice of preparations by animal species

Bi-septim

Suitable for:

turkey chicken duck goose

Bi-septim

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Bi-septim

powder for oral administration

 

Composition

1 g contains:

tylosin tartrate — 150 mg

oxytetracycline hydrochloride — 150 mg

ascorbic acid — 200 mg

 

Description

The powder of light yellow color, soluble in water.

 

Pharmacological properties

Tylosin is an antibiotic of the macrolide group, binds to the 50S ribosomal subunit and inhibits protein synthesis. Active against Gram-positive bacteria Staphylococcus spp., Streptococcus spp., Corynebacterium spp., Clostridium spp., Listeria, Erysipelothrix spp., some Gram-negative Haemophilus spp., Pasteurella spp., Actinomyces spp., Mycoplasma spp., Chlamydia spp., Ureaplasma spp., Rikettsia spp.

Oxytetracycline is a bacteriostatic antibiotic that acts on the ribosomes of bacteria, preventing the synthesis of protein. Has a wide spectrum of action on Gram-positive and Gram-negative bacteria Streptococcus spp., Staphylococcus spp., Campylobacter spp., E. coli, Haemophilus spp., Pasteurella spp., Bordetella spp., rickettsia, many strains of mycoplasmas, chlamydia and some protozoa.

Vitamin C increases resistance to infections, speeds up metabolism, is an antioxidant.

When administered orally, oxytetracycline is rapidly absorbed. After 30 minutes, its concentration in the serum is almost 60% of the therapeutic, the maximum concentration in the blood serum is achieved in 2-3 hours. Oxytetracycline is almost not metabolized in body — about 60% is excreted in urine unchanged, the rest is excreted with bile.

Tylosin is well absorbed from digestive tract, creating bacteriostatic levels in blood and tissues. Metabolized mainly in liver, excreted mainly with urine and bile.

 

Indications

It is indicated for treatment of young and adult poultry (chickens, turkeys, ducks, geese) suffering from the diseases of the gastrointestinal tract and respiratory complications of bacterial and viral diseases caused by microorganisms that are sensitive to oxytetracycline and tylosin.

 

Contraindications

Hypersensitivity to tylosin and oxytetracycline.

Do not use simultaneously with cephalosporins, penicillins, erythromycin and sulfonilamides.

Do not use for laying hens, eggs of which are used for human consumption.

 

Administration and dosage

Orally in a dose of 1 g of drug per 1 l of drinking water or feed — 2 g of drug per 1 kg of feed, treatment course — 3-5 days.

 

Warning

Slaughter of poultry for meat is allowed in 15 days after the last administration. Meat obtained before the specified period is utilized or used for unproductive animals feeding according to the conclusion of a veterinarian.

 

Packaging

Polymer packages of 10, 500 g.

 

Storage

Store in a dry, dark place at the temperature from +4 °C to +25 °C.

 

Shelf life

2 years.