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Choice of preparations by animal species

  1. horse
  2. cow
  3. goat
  4. sheep
  5. pig
  6. dog
  7. cat
  8. chicken
  9. duck
  10. goose
  11. dove
  12. сamel
  13. bee

Kefen

Suitable for:

horse cow

pig

Kefen

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Kefen

solution 10% for injection

 

Composition

1 ml contains:

ketoprofen — 100 mg

 

Description

Clear colorless solution.

 

Pharmacological properties

Non-steroidal anti-inflammatory drug (NSAID) with a pronounced analgesic and antipyretic effect.

Ketoprofen is a substance from the group of carboxylic acids, derivatives of propionic acid. The mechanism of its action is to inhibit synthesis of prostaglandins and thromboxane and is based on a violation of the metabolism of arachidonic acid. In therapeutic doses, ketoprofen inhibits mainly COX-II and partially COX-I, providing anti-inflammatory, analgesic, antipyretic and anti-endotoxic effects.

After a single intramuscular injection, the maximum concentration of ketoprofen in blood plasma is reached after 30 minutes. Ketoprofen is excreted from the body mainly by the kidneys.

 

Indications

It is indicated for treatment of cattle, pigs, horses, dogs with acute or chronic inflammatory process of the musculoskeletal system (arthritis, arthrosis, bursitis, sprains, swelling, tenosynovitis, trauma, infections of the hoof), respiratory organs, syndrome of metritis-mastitis-agalactia, various forms of mastitis, for the treatment of pain syndrome of various etiologies (after surgery, injury, colic), as an antipyretic agent in diseases accompanied by hyperthermia and depressed mood.

 

Contraindications

Do not administer to animals with hypersensitivity to the drug.

Do not administer to animals with gastric or duodenal ulcer, hemorrhagic syndrome, severe renal or hepatic insufficiency.

Do not administer simultaneously with other NSAIDs, corticosteroids, anticoagulants and diuretics.

 

Administration and dosage

The drug is administered intramuscularly or intravenously once a day in the following doses:

• cattle: intravenously or intramuscularly, 0.3 ml of drug per 10 kg of body weight during 1-3 days;

• sport horses: intravenously or intramuscularly, 1 ml of drug per 45 kg of body weight during 3-5 days (for animal treatment of colic single administration will be sufficient);

• pigs: intramuscularly, 0.3 ml of drug per 10 kg of body weight during 1-3 days.

Injections of more than 10 ml are divided into two or more portions and injected into different sites.

 

Warning

Do not mix with other drugs in the same syringe.

The slaughter of pigs for meat is allowed in 4 days, cattle — in 5 days. Meat obtained before the specified period is utilized or fed to unproductive animals depending on the conclusion of a veterinarian. Milk can be used without restrictions.

 

Packaging

Dark glass vials of 10 ml (10 pcs in a cardboard box), 100 ml (1 pc in a cardboard box).

 

Storage

Store in a dry, dark place in the original package at temperature from +4 °C to +25 °C.

 

Shelf life

2 years.